DNB ques june 2008
Anatomy 1)Deltoid ligament doesn't join med cuneiform.
2)Scalenus anterior -wrong statement-subclavian art.lies anteriorly
3)Pain along medial aspect of arm through in Ca Breast-intercostobrachial nerve
4)Laminae in substantia gelatinosa- 2+3
5)Muscle in deep perinial pouch-sphincter urethrae
6)Persistent primitive streak-Sacrococcygeal teratoma
7)Carpal tunnel syn- median nerve
8)Pudendal nerve- S2-4
9)Pelvic diaphragm consist of – levator ani
10)Lateral displacement of knee prevented by-
11)Abduction of toes is by - Dorsal interossi
12)Base of 5th metatarsal fracture pull of – Peronius brevius
13)Ext rotation in semi flexed knee all except - Fibular Collateral Ligament
14)Does not pass under extensor retinalculum - Ant interoseus artery
15)Section of fibular nerve - Foot drop
16)Not a part of epithalamus is - (parts are 1.pineal, 2.habencular nuclei,trigone &commissure 3.stria medullaris)
17)Striae of Gennari seen in - also called the "band" or "line" of Gennari is a band of myelinated axons projecting into layer 4C of the primary visual cortex from the lateral geniculate nucleus
18)Porto systemic shunt is present at A/E – Lower anal canal/or upper anal canal 19)Structure not passing through inf cerebellar peduncle – Pontocerebellar 20)Ophthalmic artery is Branch of – Intra cranial Int.carotid
21)Nucleus ambigus true is - 9th and 10th nerve arise from it.
22)Not a part of Internal Capsule – Optic radiation
23)Endinger Westphal nucleus – General visceral efferent
24)Uterine epithelium develops from - Fusion of paramesonephric ducts
25)Boundries of pudendal canal – Between obturator membrane and Facia lunata
PHYSIO
1)Circadian rhythm controlled by – Suprachismatic nucleus
2)Preganglionic sympathetic and parasympathetic secrete – acetylcholine
3)Diffusion of a molecule is directly proportional to – Mol wt/ Temperature/ Water solubility/ Thickness of membrane
4)Parasympathetic stimulation – Increase airway resistance
5)Most important Buffer in blood – Hb / protein
6)Inverse stretch reflex – Lengthening of Muscle /inhibition of antagonist muscle.
7)Myoglobin is present in – Slow Fibers
8)Inhibin causes
9)Hyperparathyroidism asso c – Increases Alk phosphatase
10)Neurosecretory peptide is – Somatostatin
11)Oxytocin – Neurophysin
12)True abt Capillaries – Large cumulative surface area/Small individual diameter/thin wall/incresed velocity
13)Estrogen secreted by – Theca cells
14)Intracellular cation most osmotically active – Na / k
15)Interstitial fluid has most imp – Na / protein
16)Splanchnic circulation – 25-30%
17)pH sensing receptors present in A/E – Jugular bulb
18)pH of blood is – 7.35 to 7.45
19)Arterial PO2 decreases in – CO poisoning/ cyanide poisoning/ anemia/ none
Biochemistry
1)HGPRT – Hypoxanthene & guanine
2)Allosteric type – bind site other than that of substrate
3)Telomerase - RNA dependant DNA polymerase
4)Degeneracy of Genetic Code – for 1 a.a. there may be more than 1 codon
5)Hormone responsive element – DNA sequence where hormone -binding protein complex binds
6)Not a w3 fatty acid – Linolic acid
7)B12 is absorbed in – Ileum
8)Protein in cell membrane can function as – Active transport/Carrier/??/ All
9)Iron present in all except – Ceruloplasmin
10)Fastest peak on electrophoresis – Adult hb/fetal hb/Bart's hb/??
11)Vit D 1,25, OH no role of - Intestine / liver
PHARMAC
1)Fatty food increases absorption of – Griseofulvin
2)Partial agonist – Can bind all receptors but produces submaximal activity
3)Which is most resistant aminoglycoside to enzyme - Amikacin
4)Requirement of iron in anaemia calculated by – 4.4*Body wt * Hb deficit
5)True about Folic acid - Required for thymidine synthesis
6)Pralidoxime C/I in – Carbaryl poisoning
7)What will not be found in urine of person consuming multivitamin tablets- Cholecalciferol
8)DOC for systemic aspergillosis – ?Iatraconazole/?Amphotericin
9)Amphotercin B toxicity is monitored by -- ?Potassium Measurement /creatinine
10)Drug that increases blood level of carbamazapine – ?Ketoconazole
11)True about Valproate is – Causes Hepatic Necrosis
12)Quinidine is asso c A/E – SLE/Tachycardia on treating AF/Bradycardia/Torsades de pointes
13)Anti-IgE used in asthma is – Omalizumab
14)Local Anaesthetic used in I.V.Local Block(Bier's) – Bupivacaine
15)Local Anaesthetic in patient with Hepatic disease – Procaine
16)The drug with agonist receptor A/E – Pentazocine/ Buprenorphine/levonorphan/??
17)BZDs in hypnotic doses consistently produce – Decrease BP/Reduces nocturnal acid secretion/respi depression/??
18)True about Cefuroxime – excreted rapidly by kidneys
19)Granisetron – 5HT3 antagonist
20)Antiparkinsonian drug c antiapoptotic activity -- Selegeline
Pathology
1) Delayed type of hypersensitivity is asso c – Memory CD4 cells
2)Not a mediator in allergic rhinitis – CD4/SRS-a/Brsdykinin/Leukotreines
3)Cells like Reed Steinberg are seen in – Inf mononucleosis/mycosis fungoides/solid tissue cancer/all of the above
4)Programmed cell death is called – Apoptosis
5)Apoptosis true is – Cell self initiated
6)HMB45 is tumour marker of – Melanoma/Angiomyolipoma/??/All
7)Barr body first detected in - ?buccal mucosa/brain/liver/skin
8)Stable cells – hepatocytes
9)Falciparum binds to which receptor molecule in brain vascular endothelium – ICAM 1
10)Following is not a tumour marker – CEA/AFP/HCG/(thus last option is answer)
11)Alcoholism seen is – Raised ALT i.e. SGPT
12)Thrombosthenin is – contractile protein of platelets
13)Cryoprecipitate contains – Factor VIII and fibrinogen (Remember also vWF)
MICRO-BIOLOGY
1)True about Hepatitis A virus is A/E – Carrier rate 2%
2)Yellow fever virus is – Flavi virus
3)Acute HIV infection is diagnosed – p24 Ag capture assay
4)SARS is – Corona virus
5)Not a RNA virus – Hepatitis B
6)Mad Cow disease – protein-prion
7)TSS caused by – Staph. Aureus
8)Infant botulinism true A/E – preformed toxin
9)Superantigens A/E – Staph. Endotoxin
10) Lysogenic conversion – Diphtheria
11)MC streptococcus in neonatal meningitis – Lancefield Group B
12)Lipophilic fungus - ??cryptococcus
13)Cryptococcus diagnostic test – India ink
14)Yeast form in tissue A/E – Aspergiilus
15) Diagnostic in 1st week of typhoid – blood culture
16)Typhoid incubation period – 3 -21 days
17)Perforation in typhoid commonly -3rd week
18)Petroff method for sputum microscopy – Concentration method that don't kill bacteria, Incubation c 4% NaOH at 370 C --> Centrifugation at 3000 rpm for 20 min-->Neutralisation c N/10 HCL, Useful for culture & animal inoculation.
19)Vibrio cholerae is characteristic for – growth in alkaline medium
20)True about Pseaudomonas aeuruginosa A/E-- relatively sensitive to many antimicrobials
21)Congenital toxoplasmosis occurs if – infection acquired in later half of pregnancy in non immune mother
Forensic
1)Acrodynia – Hg
2)Drug and Cosmetic Act-import,manufacture,distibution,[no ads please] of all drugs.. controls quality,purity
& strength.
3)Contributory negligence- ??avoidable circumstance rule
4)Boiled lobster appearance seen in- boric acid/oxalic acid/??
5)Common toxin through vegetables –???oxalic/carbolic/etc
6)Juvenile court -1st class magistate (must be) Female
7)Instead of penicillamine can be used in cu poisionong – Edta
8)Some law related with cadaveric spasm
9)Chilotic line – seen on hip bone for sex determination
10)Test with inverted fer tree appearance – ?sperm in vagina
11)Cholenesterae seen in – elapide mainly i. e. cobra crates , viperade crotalide some amount
PSM
1)Neonatal tetanus eliminated when incidence – is Less than 0.1/ 1000
2)Contribution of employer in ESIS – 4.75%
3)Clorination of water criteria – Clear water
4)Rat flea – Endemic typhus
5)Not transmitted by mosquito – Kala azar
6)Epidemiological investigation of choce for kala azar - ELISA /Montenegro test/ Aldehyde test/??
7)Natural mosquito control agent – Pyrethrum
8)reading of abraded skin by dog – Class 2 – So Vaccine only
9)Sullivan's index-life free of disability
10)Entry of pathogen & maximum infectivity-Generation time
11)Definitive diagnosis of leprosy – skin smear
12)Antigenic shift is in – influenza
13)True of carrier in typhoid – urinary carrier with anomaly
14)Shortest incubation period in food poisioning – Staph aureus
15)Chandler's index – ankylostoma duodenle
16)Drakunculosis transmitted by – Drinking Contaminated water
17)Multibacillary Leprosy is followed upto – 5 Years
18)The concept of Female Health guide was given by – Kartar Singh
19)Socrate's method of health education is by – ?Didactic method/Group discussion
20)Best guide of iron defiency – Serum ferritin
21)Different communities best compared by – Age specific death rate
22)Burden of disease formula – (Positives/Tested)*Population
23)Comfortable temp range – 77-80F
24)Mother to be labelled high risk – Ht less than 140cm
25)Efficiency of Malaria elimination program is evaluated using – ABER
26)Prophylaxis to maniac person not on medication coming to Bihar - ??Mefloquine
27)Percentage of para para in DDT-- 70-80%
28)Corpulence index used in – Obesity
29)Correct statement – ans-Population density 324/sq km / TFR- 6/ growth ratio – 2.2/??
ENT
1)Kisselbach's plexus – Plexus of arteris in ant septum(littele's area)
2)Quadrilteral cartilage – Ant part of septum
3)Young's syndrome – Nasal polyp, bronchiectasis, azoospermia
4)True about A/C polyp – Single seen in choana
5)Sphenoid sinus drains into – Sphenoethmoidal recess
6)Drainage of nasal mucous – Cilliary action of Mucosa
7)Inferior turbinate – is a separate bone
8)In FESS C.T. Scan is advised-??
9)Caldwell-Luc's operation – For Maxillary sinus
10)Nasal bone # corrected by- Walsham's forceps
11)Aspirin use is asso. With - Nasal polyps
12)All sinuses are best viewed in – Caldwel's view/Water's view/Trans orbital view
13)Nerve coming out of Stylomastoid foramen – Facial
14)Epulis is sweling from – Jaw
15)MC cause of fungal Oesophagitis – candida
OPHTHALM
1)Intermittent proptosis – orbital varices
2)Most dangerous injury for vision - # Optic nerve canal
3)Corneal ectasia with inflammation – Ant Staphyloma
4)Keratoconus is not asso with – Hypermetropia
5)Osteosclerosis of orbit – Meningioma/retinoblastoma/?
6)Rees-Elsworth classification – Retinoblastoma
7)Large choroidoma is asso with - ??
8)Pars planitis visual loss due to – CME
9)Facial paralysis epiphora due to - ??
10)Corneal Ulcer C/I in Rx - Corticosteroids
11)Photoreceptor on stimulated release –Glutamate
12)MC cause of blindness in India – Cataract
13)Thyroid ophthalmopathy MRI finding swelling of – Origin/Insertion/Whole belly
14)Endogenous fungal panophthalmitis - ?Aspergillous
15)Aphakic eye finding A/E – 8% Magnification
Obs -GYN
1)At term amniotic fluid volume is – 800ml
2)Amniotic fluid contain - ~Glucose/?Fructose/?Mannose/?Galactose
3)Oligohydramnios - Renal Agenesis
4)Early amniocentesis -12-14wks
5)Immune rejection of fetus prevented by - HCG
6)Pre-eclampsia GFR -Decreases.
7)Fetal adrenals secrete -Cortisol/DHEA/??
8)Shortest diameter of Cavity- Interspinous
9)Large Chorioangioma asso with - polyhydroamnios
10)Commonest presentation of Choriocarcinoma – bleeding
11)Frog eye appearance – Anencephaly
12)Partial mole -Triploidy
13)Cervical change pregnancy- incre.collagen/incre.Hyluronic acid/Incr.glands
14)10U of Oxytcin bolus imm.complication- Hypotension
15)Oxytocin levels not reduced by – Suckling
16)Latzko operation – VVF
17)Drug contraindicated in pregnancy- enalpril
18)Not a tocolytic – Misopristol
19)Not a steroid synthesis inhibitor – Mifepristone
20)IUD Failure rate – 1 to 3/less than 1???
21)Ovarian tumour spread – Para aortic node
22)Folic acid supplement required in pregnancy – Anti convulsant therapy/ Sickle cell anemia/ Multiple gestation/ All of the above
23)30 yr old female with endometrial hyperplasia DOC- medroxyprogesterone
24)HELLP syndrome recurrence rate - ? 2%
SURGERY
1)Hydatid cyst scolicidal agent not used – Povidone
2)Barret's Osophagus is – Metaplasia
3)Not used Breast Ca – Bleomycin
4)RCC not true is – Common in women/ Radiosensitive
5)Acute papillary tip necrosis – Diabetes Mellitus
6)Risk of thromoembolism is highest with – Femoral vein thrombus
7)Hyoid bone is related to – Thyroglossal cyst
8)Young woman who received mantle radiation in childhood is likely to develop – Ca thyroid/ Ca Breast
9)FNAC in testies is indicated in – Azoospermia to identify cause/Necrospermia/Differentiate between torsion and inflammation/ all of above--????
10)Vaginal hydrocele is open upto – Upper pole of testies
11)Excessive catabolism seen in – Severe sepsis/Pancreatitis/??/All
12)Mesothelioma- Decreasing incidence reflects ban on use asbestos
13)Clot of size of fist accounts for blood loss of – 500ml
14)Family history is not asso with – Lung cancer
15)Renal Imaging in pt with allergy – USG
16)MC site of Actinomycetes – jaw
17)Watermelon Stomach -
18)BRCA gene positive Breast Ca – Good prognosis to radiotherapy/bad prognosis to radiotherapy/bad prognosis to chemotherapy
19)In a child with gastric outlet obstruction fluid used – Normal saline/Ringer lactate/dextrose
20)Narrowest part of male urethra – Meatus Ext.
21)Middle aged man with renal failure with B/L abdominal mass – ADPKD
22)Lung injury with good prognosis – Open pneumothorax
23)All causes of painless haematuria except – Acute Cystitis
24)Spindle cell tumour is – Retroperitoneal fibrosis in infants/??
25)What is true abt prostate Ca – 30% of all malignancies in male/10% incidence in general population/??
26)True abt PSA – Lipoprotein/Measured by immunoassay/Sensitive and specific to differentiate between Ca & BPH
27)Curling ulcer is asso with – Burns
28)Hashimoto's thyroiditis – Auto Ig present / Always presents with hyperthyroidism/??
29)Raynaud's phenomenon sequence – Pallor , Cyanosis , Rubor
30)Ca not spreading by lymphatics – Basal Cell Carcinoma
31)Increase in risk of colorectal cancer – Low fiber diet
32)Most radio sensitive – Bone marrow
33)Breast cancer related with – Early menarche
34)Not used for hemostasis in surgery – gel foam/micronised cellulose/micronised collagen/
35)highest prognostic value in breast cancer – H/O ca in contralateral breast.
36)Complication of epidural Anaesthesia A/E– cord compression/low volume headache/backache/meningitis
37)Total spinal Anaesthesia seen A/E – hypotension/tachycardia/respiratory depression/unconsciousness
orthopaedics
1)Stress # of- 2nd metatarsal
2)# Neck of femur- Ext rotation and adduction
3)Tuberculous spine mc site- T12/L1
4)Tuberculous arthritis first sign- reduced jt space
5)PID investigation of choice- MRI
6)Clutton jt MC cause- Diabetes Mellitus
7)Neuropathic jt not seen in – DM /amyloidosis/leprosy/sarcoidosis
8)Dactylitis not seen in- sarcoidosis/psoriatic arthritis/tuberculosis/reactive arthritis
9)Standing on toes not possible in paralysis of- Gastrocnemius
10)Card test- Ulnar Nerve
11)Onion peel appearance – Ewig's sarcoma
12)Rheumatoid affect axial skeleton – cervical vertebrae
13)AVN commonly in – intra capsular # NOF
14)Treatment of choice for postmenopausal osteoporosis- Raloxefine
15)Nerve regeneration – 1 mm/day
MEDICINE
1)Displacement of Apex to Lt. And downward – LVH
2)Sinus Bradycardia – less than 60
3)Blood culture is diagnostic in – Infective endocarditis
4)MCC of infective endocarditis – Strepto Viridans
5)Atherosclerosis asso. Infection – Chlymadia pneumonae
6)Osler's nodes – SABE
7)CPAP asso c A/E – Incresed Cardiac output
8)Systolic murmur asso c – Ejection click
9)Physiologocal murmur asso c A/E – Distolic murmur
10)Conn's syndrome – Hyperaldosteronism c Hypokalemia
11)Pure red cell aplasia is asso c - Thymoma
12)Exogenous insulin is differentiated from endogenous by – Presence of 'C' peptide
13)Metabolic syndrome is asso c A/E – Incre HDL
14)Chynes Stokes breathing – Metabolic alkolosis
15)Granulomatous condition with hypercalcemia – Sarcoidosis
16)Apoplexy – Sudden attack of Paralysis
17)Viral Meningitis not asso c – Normal Sugar/Normal chloride/Lymphocytes/Decreased proteins
18)CRF anaemia due to – Erythropoietin deficiency
19)Autosomal Dominant A/E – Beta thallasemia
20)MC cause of Secondary HTN – Renovascular disease
21)Refractory HTN commonest cause – Pt non compliance/Drug induced/ Pheochromocytoma
22)Hypokalemia produces ECG changes A/E – Tall 'T' waves
23)Angina duration – 1-5mins/5-10mins/15mins/30mins
24)Unstable angina – Crescendo with normal ECG
25)Sino atrial disease – Atrial ectopic/Ventricular ectopic/Sinus arrest/Sinus Arrythmia
26)Repeat as above
27)Adenoma Sebaceum in Tuberous Sclerosis is – Angiofibroma
28)Drug induced lupus- anti histone antibodies
29)Portwine urine seen in – porphyria/ nephritis/melanoma/ All of the above
30)Nephritis syndrome A/E – Hypertension/ Hematuria/oliguria/oedema
31)Hepatic carcinogen is – Aflatoxin
32)Liver cirrhosis is d/t – Galactosemia
33)Parentral fat nutrition c/i – Hyperlipidemia/DM /thrombotic states/All
34)Prophylaxis of pneumocystis carinii advised – AIDS/Symtomatic HIV/asymptomatic HIV/acute HIV
35)Pneumocystis carinii pneumonia - ?inter-alveolar septum
36)Normal urinary protein excretion - <150mg/150-200/200-250/250-300
37)Loud P2 is with - Pulmonary HTN
38)Hydropic degeneration of Basal Cell seen in –Lichen planus/Lichen sclerosis atrphicus/??/??/
PEDIATRICS
1)Nada's criteria for – heart disease
2)TOF radiological features A/E - ??Rt sided arch of Aorta
3)Single Umbilical artery is asso with cong anomalies – 10-20%
4)The organ in Child with same size as adult – Pituitary/Eye/Adrenal/thymus
5)Brown fat is present in A/E – Cheek
6)Fore milk contain A/E – Fat
7)MC valve asso with Rheumatic affection – Mitral
8)Ratio of chest compression to breath in child – 3:1
9)Thallasemia faces not present – Anti mongoloid slant
10)1 yr baby with diarrhoea flushing , bone pain, fullness in flanks- neuroblastoma
11)Fetal hemoglobin – α2/γ2
12)Brain to liver ratio in malnourished – 1:2/3:1/2:1/5:1
13)Hypsrrythmia seen in – West syndrome{infantile spasm}
Psychiatry
1)Commonest psychiatric diagnosis – Depression
2)Psychosis is asso with – Delusion
3)In a patient with mania drugs to be used is – Mood stabilizer
4)Excessive buying is called – Oniomania
2)Scalenus anterior -wrong statement-subclavian art.lies anteriorly
3)Pain along medial aspect of arm through in Ca Breast-intercostobrachial nerve
4)Laminae in substantia gelatinosa- 2+3
5)Muscle in deep perinial pouch-sphincter urethrae
6)Persistent primitive streak-Sacrococcygeal teratoma
7)Carpal tunnel syn- median nerve
8)Pudendal nerve- S2-4
9)Pelvic diaphragm consist of – levator ani
10)Lateral displacement of knee prevented by-
11)Abduction of toes is by - Dorsal interossi
12)Base of 5th metatarsal fracture pull of – Peronius brevius
13)Ext rotation in semi flexed knee all except - Fibular Collateral Ligament
14)Does not pass under extensor retinalculum - Ant interoseus artery
15)Section of fibular nerve - Foot drop
16)Not a part of epithalamus is - (parts are 1.pineal, 2.habencular nuclei,trigone &commissure 3.stria medullaris)
17)Striae of Gennari seen in - also called the "band" or "line" of Gennari is a band of myelinated axons projecting into layer 4C of the primary visual cortex from the lateral geniculate nucleus
18)Porto systemic shunt is present at A/E – Lower anal canal/or upper anal canal 19)Structure not passing through inf cerebellar peduncle – Pontocerebellar 20)Ophthalmic artery is Branch of – Intra cranial Int.carotid
21)Nucleus ambigus true is - 9th and 10th nerve arise from it.
22)Not a part of Internal Capsule – Optic radiation
23)Endinger Westphal nucleus – General visceral efferent
24)Uterine epithelium develops from - Fusion of paramesonephric ducts
25)Boundries of pudendal canal – Between obturator membrane and Facia lunata
PHYSIO
1)Circadian rhythm controlled by – Suprachismatic nucleus
2)Preganglionic sympathetic and parasympathetic secrete – acetylcholine
3)Diffusion of a molecule is directly proportional to – Mol wt/ Temperature/ Water solubility/ Thickness of membrane
4)Parasympathetic stimulation – Increase airway resistance
5)Most important Buffer in blood – Hb / protein
6)Inverse stretch reflex – Lengthening of Muscle /inhibition of antagonist muscle.
7)Myoglobin is present in – Slow Fibers
8)Inhibin causes
9)Hyperparathyroidism asso c – Increases Alk phosphatase
10)Neurosecretory peptide is – Somatostatin
11)Oxytocin – Neurophysin
12)True abt Capillaries – Large cumulative surface area/Small individual diameter/thin wall/incresed velocity
13)Estrogen secreted by – Theca cells
14)Intracellular cation most osmotically active – Na / k
15)Interstitial fluid has most imp – Na / protein
16)Splanchnic circulation – 25-30%
17)pH sensing receptors present in A/E – Jugular bulb
18)pH of blood is – 7.35 to 7.45
19)Arterial PO2 decreases in – CO poisoning/ cyanide poisoning/ anemia/ none
Biochemistry
1)HGPRT – Hypoxanthene & guanine
2)Allosteric type – bind site other than that of substrate
3)Telomerase - RNA dependant DNA polymerase
4)Degeneracy of Genetic Code – for 1 a.a. there may be more than 1 codon
5)Hormone responsive element – DNA sequence where hormone -binding protein complex binds
6)Not a w3 fatty acid – Linolic acid
7)B12 is absorbed in – Ileum
8)Protein in cell membrane can function as – Active transport/Carrier/??/ All
9)Iron present in all except – Ceruloplasmin
10)Fastest peak on electrophoresis – Adult hb/fetal hb/Bart's hb/??
11)Vit D 1,25, OH no role of - Intestine / liver
PHARMAC
1)Fatty food increases absorption of – Griseofulvin
2)Partial agonist – Can bind all receptors but produces submaximal activity
3)Which is most resistant aminoglycoside to enzyme - Amikacin
4)Requirement of iron in anaemia calculated by – 4.4*Body wt * Hb deficit
5)True about Folic acid - Required for thymidine synthesis
6)Pralidoxime C/I in – Carbaryl poisoning
7)What will not be found in urine of person consuming multivitamin tablets- Cholecalciferol
8)DOC for systemic aspergillosis – ?Iatraconazole/?Amphotericin
9)Amphotercin B toxicity is monitored by -- ?Potassium Measurement /creatinine
10)Drug that increases blood level of carbamazapine – ?Ketoconazole
11)True about Valproate is – Causes Hepatic Necrosis
12)Quinidine is asso c A/E – SLE/Tachycardia on treating AF/Bradycardia/Torsades de pointes
13)Anti-IgE used in asthma is – Omalizumab
14)Local Anaesthetic used in I.V.Local Block(Bier's) – Bupivacaine
15)Local Anaesthetic in patient with Hepatic disease – Procaine
16)The drug with agonist receptor A/E – Pentazocine/ Buprenorphine/levonorphan/??
17)BZDs in hypnotic doses consistently produce – Decrease BP/Reduces nocturnal acid secretion/respi depression/??
18)True about Cefuroxime – excreted rapidly by kidneys
19)Granisetron – 5HT3 antagonist
20)Antiparkinsonian drug c antiapoptotic activity -- Selegeline
Pathology
1) Delayed type of hypersensitivity is asso c – Memory CD4 cells
2)Not a mediator in allergic rhinitis – CD4/SRS-a/Brsdykinin/Leukotreines
3)Cells like Reed Steinberg are seen in – Inf mononucleosis/mycosis fungoides/solid tissue cancer/all of the above
4)Programmed cell death is called – Apoptosis
5)Apoptosis true is – Cell self initiated
6)HMB45 is tumour marker of – Melanoma/Angiomyolipoma/??/All
7)Barr body first detected in - ?buccal mucosa/brain/liver/skin
8)Stable cells – hepatocytes
9)Falciparum binds to which receptor molecule in brain vascular endothelium – ICAM 1
10)Following is not a tumour marker – CEA/AFP/HCG/(thus last option is answer)
11)Alcoholism seen is – Raised ALT i.e. SGPT
12)Thrombosthenin is – contractile protein of platelets
13)Cryoprecipitate contains – Factor VIII and fibrinogen (Remember also vWF)
MICRO-BIOLOGY
1)True about Hepatitis A virus is A/E – Carrier rate 2%
2)Yellow fever virus is – Flavi virus
3)Acute HIV infection is diagnosed – p24 Ag capture assay
4)SARS is – Corona virus
5)Not a RNA virus – Hepatitis B
6)Mad Cow disease – protein-prion
7)TSS caused by – Staph. Aureus
8)Infant botulinism true A/E – preformed toxin
9)Superantigens A/E – Staph. Endotoxin
10) Lysogenic conversion – Diphtheria
11)MC streptococcus in neonatal meningitis – Lancefield Group B
12)Lipophilic fungus - ??cryptococcus
13)Cryptococcus diagnostic test – India ink
14)Yeast form in tissue A/E – Aspergiilus
15) Diagnostic in 1st week of typhoid – blood culture
16)Typhoid incubation period – 3 -21 days
17)Perforation in typhoid commonly -3rd week
18)Petroff method for sputum microscopy – Concentration method that don't kill bacteria, Incubation c 4% NaOH at 370 C --> Centrifugation at 3000 rpm for 20 min-->Neutralisation c N/10 HCL, Useful for culture & animal inoculation.
19)Vibrio cholerae is characteristic for – growth in alkaline medium
20)True about Pseaudomonas aeuruginosa A/E-- relatively sensitive to many antimicrobials
21)Congenital toxoplasmosis occurs if – infection acquired in later half of pregnancy in non immune mother
Forensic
1)Acrodynia – Hg
2)Drug and Cosmetic Act-import,manufacture,distibution,[no ads please] of all drugs.. controls quality,purity
& strength.
3)Contributory negligence- ??avoidable circumstance rule
4)Boiled lobster appearance seen in- boric acid/oxalic acid/??
5)Common toxin through vegetables –???oxalic/carbolic/etc
6)Juvenile court -1st class magistate (must be) Female
7)Instead of penicillamine can be used in cu poisionong – Edta
8)Some law related with cadaveric spasm
9)Chilotic line – seen on hip bone for sex determination
10)Test with inverted fer tree appearance – ?sperm in vagina
11)Cholenesterae seen in – elapide mainly i. e. cobra crates , viperade crotalide some amount
PSM
1)Neonatal tetanus eliminated when incidence – is Less than 0.1/ 1000
2)Contribution of employer in ESIS – 4.75%
3)Clorination of water criteria – Clear water
4)Rat flea – Endemic typhus
5)Not transmitted by mosquito – Kala azar
6)Epidemiological investigation of choce for kala azar - ELISA /Montenegro test/ Aldehyde test/??
7)Natural mosquito control agent – Pyrethrum
8)reading of abraded skin by dog – Class 2 – So Vaccine only
9)Sullivan's index-life free of disability
10)Entry of pathogen & maximum infectivity-Generation time
11)Definitive diagnosis of leprosy – skin smear
12)Antigenic shift is in – influenza
13)True of carrier in typhoid – urinary carrier with anomaly
14)Shortest incubation period in food poisioning – Staph aureus
15)Chandler's index – ankylostoma duodenle
16)Drakunculosis transmitted by – Drinking Contaminated water
17)Multibacillary Leprosy is followed upto – 5 Years
18)The concept of Female Health guide was given by – Kartar Singh
19)Socrate's method of health education is by – ?Didactic method/Group discussion
20)Best guide of iron defiency – Serum ferritin
21)Different communities best compared by – Age specific death rate
22)Burden of disease formula – (Positives/Tested)*Population
23)Comfortable temp range – 77-80F
24)Mother to be labelled high risk – Ht less than 140cm
25)Efficiency of Malaria elimination program is evaluated using – ABER
26)Prophylaxis to maniac person not on medication coming to Bihar - ??Mefloquine
27)Percentage of para para in DDT-- 70-80%
28)Corpulence index used in – Obesity
29)Correct statement – ans-Population density 324/sq km / TFR- 6/ growth ratio – 2.2/??
ENT
1)Kisselbach's plexus – Plexus of arteris in ant septum(littele's area)
2)Quadrilteral cartilage – Ant part of septum
3)Young's syndrome – Nasal polyp, bronchiectasis, azoospermia
4)True about A/C polyp – Single seen in choana
5)Sphenoid sinus drains into – Sphenoethmoidal recess
6)Drainage of nasal mucous – Cilliary action of Mucosa
7)Inferior turbinate – is a separate bone
8)In FESS C.T. Scan is advised-??
9)Caldwell-Luc's operation – For Maxillary sinus
10)Nasal bone # corrected by- Walsham's forceps
11)Aspirin use is asso. With - Nasal polyps
12)All sinuses are best viewed in – Caldwel's view/Water's view/Trans orbital view
13)Nerve coming out of Stylomastoid foramen – Facial
14)Epulis is sweling from – Jaw
15)MC cause of fungal Oesophagitis – candida
OPHTHALM
1)Intermittent proptosis – orbital varices
2)Most dangerous injury for vision - # Optic nerve canal
3)Corneal ectasia with inflammation – Ant Staphyloma
4)Keratoconus is not asso with – Hypermetropia
5)Osteosclerosis of orbit – Meningioma/retinoblastoma/?
6)Rees-Elsworth classification – Retinoblastoma
7)Large choroidoma is asso with - ??
8)Pars planitis visual loss due to – CME
9)Facial paralysis epiphora due to - ??
10)Corneal Ulcer C/I in Rx - Corticosteroids
11)Photoreceptor on stimulated release –Glutamate
12)MC cause of blindness in India – Cataract
13)Thyroid ophthalmopathy MRI finding swelling of – Origin/Insertion/Whole belly
14)Endogenous fungal panophthalmitis - ?Aspergillous
15)Aphakic eye finding A/E – 8% Magnification
Obs -GYN
1)At term amniotic fluid volume is – 800ml
2)Amniotic fluid contain - ~Glucose/?Fructose/?Mannose/?Galactose
3)Oligohydramnios - Renal Agenesis
4)Early amniocentesis -12-14wks
5)Immune rejection of fetus prevented by - HCG
6)Pre-eclampsia GFR -Decreases.
7)Fetal adrenals secrete -Cortisol/DHEA/??
8)Shortest diameter of Cavity- Interspinous
9)Large Chorioangioma asso with - polyhydroamnios
10)Commonest presentation of Choriocarcinoma – bleeding
11)Frog eye appearance – Anencephaly
12)Partial mole -Triploidy
13)Cervical change pregnancy- incre.collagen/incre.Hyluronic acid/Incr.glands
14)10U of Oxytcin bolus imm.complication- Hypotension
15)Oxytocin levels not reduced by – Suckling
16)Latzko operation – VVF
17)Drug contraindicated in pregnancy- enalpril
18)Not a tocolytic – Misopristol
19)Not a steroid synthesis inhibitor – Mifepristone
20)IUD Failure rate – 1 to 3/less than 1???
21)Ovarian tumour spread – Para aortic node
22)Folic acid supplement required in pregnancy – Anti convulsant therapy/ Sickle cell anemia/ Multiple gestation/ All of the above
23)30 yr old female with endometrial hyperplasia DOC- medroxyprogesterone
24)HELLP syndrome recurrence rate - ? 2%
SURGERY
1)Hydatid cyst scolicidal agent not used – Povidone
2)Barret's Osophagus is – Metaplasia
3)Not used Breast Ca – Bleomycin
4)RCC not true is – Common in women/ Radiosensitive
5)Acute papillary tip necrosis – Diabetes Mellitus
6)Risk of thromoembolism is highest with – Femoral vein thrombus
7)Hyoid bone is related to – Thyroglossal cyst
8)Young woman who received mantle radiation in childhood is likely to develop – Ca thyroid/ Ca Breast
9)FNAC in testies is indicated in – Azoospermia to identify cause/Necrospermia/Differentiate between torsion and inflammation/ all of above--????
10)Vaginal hydrocele is open upto – Upper pole of testies
11)Excessive catabolism seen in – Severe sepsis/Pancreatitis/??/All
12)Mesothelioma- Decreasing incidence reflects ban on use asbestos
13)Clot of size of fist accounts for blood loss of – 500ml
14)Family history is not asso with – Lung cancer
15)Renal Imaging in pt with allergy – USG
16)MC site of Actinomycetes – jaw
17)Watermelon Stomach -
18)BRCA gene positive Breast Ca – Good prognosis to radiotherapy/bad prognosis to radiotherapy/bad prognosis to chemotherapy
19)In a child with gastric outlet obstruction fluid used – Normal saline/Ringer lactate/dextrose
20)Narrowest part of male urethra – Meatus Ext.
21)Middle aged man with renal failure with B/L abdominal mass – ADPKD
22)Lung injury with good prognosis – Open pneumothorax
23)All causes of painless haematuria except – Acute Cystitis
24)Spindle cell tumour is – Retroperitoneal fibrosis in infants/??
25)What is true abt prostate Ca – 30% of all malignancies in male/10% incidence in general population/??
26)True abt PSA – Lipoprotein/Measured by immunoassay/Sensitive and specific to differentiate between Ca & BPH
27)Curling ulcer is asso with – Burns
28)Hashimoto's thyroiditis – Auto Ig present / Always presents with hyperthyroidism/??
29)Raynaud's phenomenon sequence – Pallor , Cyanosis , Rubor
30)Ca not spreading by lymphatics – Basal Cell Carcinoma
31)Increase in risk of colorectal cancer – Low fiber diet
32)Most radio sensitive – Bone marrow
33)Breast cancer related with – Early menarche
34)Not used for hemostasis in surgery – gel foam/micronised cellulose/micronised collagen/
35)highest prognostic value in breast cancer – H/O ca in contralateral breast.
36)Complication of epidural Anaesthesia A/E– cord compression/low volume headache/backache/meningitis
37)Total spinal Anaesthesia seen A/E – hypotension/tachycardia/respiratory depression/unconsciousness
orthopaedics
1)Stress # of- 2nd metatarsal
2)# Neck of femur- Ext rotation and adduction
3)Tuberculous spine mc site- T12/L1
4)Tuberculous arthritis first sign- reduced jt space
5)PID investigation of choice- MRI
6)Clutton jt MC cause- Diabetes Mellitus
7)Neuropathic jt not seen in – DM /amyloidosis/leprosy/sarcoidosis
8)Dactylitis not seen in- sarcoidosis/psoriatic arthritis/tuberculosis/reactive arthritis
9)Standing on toes not possible in paralysis of- Gastrocnemius
10)Card test- Ulnar Nerve
11)Onion peel appearance – Ewig's sarcoma
12)Rheumatoid affect axial skeleton – cervical vertebrae
13)AVN commonly in – intra capsular # NOF
14)Treatment of choice for postmenopausal osteoporosis- Raloxefine
15)Nerve regeneration – 1 mm/day
MEDICINE
1)Displacement of Apex to Lt. And downward – LVH
2)Sinus Bradycardia – less than 60
3)Blood culture is diagnostic in – Infective endocarditis
4)MCC of infective endocarditis – Strepto Viridans
5)Atherosclerosis asso. Infection – Chlymadia pneumonae
6)Osler's nodes – SABE
7)CPAP asso c A/E – Incresed Cardiac output
8)Systolic murmur asso c – Ejection click
9)Physiologocal murmur asso c A/E – Distolic murmur
10)Conn's syndrome – Hyperaldosteronism c Hypokalemia
11)Pure red cell aplasia is asso c - Thymoma
12)Exogenous insulin is differentiated from endogenous by – Presence of 'C' peptide
13)Metabolic syndrome is asso c A/E – Incre HDL
14)Chynes Stokes breathing – Metabolic alkolosis
15)Granulomatous condition with hypercalcemia – Sarcoidosis
16)Apoplexy – Sudden attack of Paralysis
17)Viral Meningitis not asso c – Normal Sugar/Normal chloride/Lymphocytes/Decreased proteins
18)CRF anaemia due to – Erythropoietin deficiency
19)Autosomal Dominant A/E – Beta thallasemia
20)MC cause of Secondary HTN – Renovascular disease
21)Refractory HTN commonest cause – Pt non compliance/Drug induced/ Pheochromocytoma
22)Hypokalemia produces ECG changes A/E – Tall 'T' waves
23)Angina duration – 1-5mins/5-10mins/15mins/30mins
24)Unstable angina – Crescendo with normal ECG
25)Sino atrial disease – Atrial ectopic/Ventricular ectopic/Sinus arrest/Sinus Arrythmia
26)Repeat as above
27)Adenoma Sebaceum in Tuberous Sclerosis is – Angiofibroma
28)Drug induced lupus- anti histone antibodies
29)Portwine urine seen in – porphyria/ nephritis/melanoma/ All of the above
30)Nephritis syndrome A/E – Hypertension/ Hematuria/oliguria/oedema
31)Hepatic carcinogen is – Aflatoxin
32)Liver cirrhosis is d/t – Galactosemia
33)Parentral fat nutrition c/i – Hyperlipidemia/DM /thrombotic states/All
34)Prophylaxis of pneumocystis carinii advised – AIDS/Symtomatic HIV/asymptomatic HIV/acute HIV
35)Pneumocystis carinii pneumonia - ?inter-alveolar septum
36)Normal urinary protein excretion - <150mg/150-200/200-250/250-300
37)Loud P2 is with - Pulmonary HTN
38)Hydropic degeneration of Basal Cell seen in –Lichen planus/Lichen sclerosis atrphicus/??/??/
PEDIATRICS
1)Nada's criteria for – heart disease
2)TOF radiological features A/E - ??Rt sided arch of Aorta
3)Single Umbilical artery is asso with cong anomalies – 10-20%
4)The organ in Child with same size as adult – Pituitary/Eye/Adrenal/thymus
5)Brown fat is present in A/E – Cheek
6)Fore milk contain A/E – Fat
7)MC valve asso with Rheumatic affection – Mitral
8)Ratio of chest compression to breath in child – 3:1
9)Thallasemia faces not present – Anti mongoloid slant
10)1 yr baby with diarrhoea flushing , bone pain, fullness in flanks- neuroblastoma
11)Fetal hemoglobin – α2/γ2
12)Brain to liver ratio in malnourished – 1:2/3:1/2:1/5:1
13)Hypsrrythmia seen in – West syndrome{infantile spasm}
Psychiatry
1)Commonest psychiatric diagnosis – Depression
2)Psychosis is asso with – Delusion
3)In a patient with mania drugs to be used is – Mood stabilizer
4)Excessive buying is called – Oniomania
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